FP6 priority

1.1.6   Sustainable Development, Global Change and Ecosystems

1.6.3

Title of the proposal

Expression of catalases and biodiversity of microorganisms as a response to oxidative stress of environment.

Institute

Slovak Academy of Sciences, Institute of Molecular Biology
Dubravska cesta 21, SK-842 51 Bratislava, Slovak Republic

Contact

Research subject for a potential FP6 project

- Expression of catalases involved in protection of microorganisms against oxidative stress (organic pollution, etc. ..)
- Investigation of catalase I from the soil bacterium Comamonas terrigena N3H, its molecular characteristics
- Screening of microbial catalases by means of PCR. The relationship of gene diversity and adaptation of microorganisms to environment.
- Evolutionary study of bacterial catalases.
- Use of catalases for practical purposes (bioremediation, medicine, etc. ).

Recent international cooperation of the research team

Institute of Biochemistry and Molecular Cell Biology, University of Vienna
Institute of Chemical Technology, Prague, Czech Republic

Proposer´s relevant publications related to the research subject

Polek,B.,Zamocky,M., Godocikova,J.,Koller,F. (2000) Stress-induced expression and partial purification of catalase-peroxidase from the soil bacteria Comamonas terrigena N3H. Chem.Listy,94, 575-576.
Zamocky,M., Godocikova,J., Koller,F., Polek,B.(2001) Potential application of catalase-peroxidase from Comamonas terrigena N3H in the biodegradation of phenolic compounds. Antonie van Leeuwenhoek, 79, 109-117.
Zamocky,M.,Janecek,S., Koller,F. (2000) Common phylogeny of catalase-peroxidases and ascorbate peroxidases. Gene,256, 169-182.