The SAS proposals for participation in FP6 projects
are listed in blocks according to the FP6 priority theme structure

Title of the proposals
1: 1.1.1
Life Sciences, Genomics and Biotechnology for Health
Genetic and immunological variability of Borrelia burgdorferi sensu lato from different geographical and biological sources of Central Europe
Role of postischemic disturbances in protein synthesis on the metabolic and functional recovery of CNS. Mechanisms of protein synthesis inhibition in the selectively vulnerable brain regions
Properties and regulation of T-type calcium channel.
Neurogenesis and ependymal cells transformation regularities in newborn, adult and aged rodents in health and pathology
The role of NO/cGMP signaling pathway in neurodegenerative disorders: ischemia-reperfusion, trauma
The origin, course and termination of truncospinal premotor nitric oxide synthase immunoreactive pathways in the spinal cord
Nitric oxide and pathomechanisms of white matter damage after traumatic spinal cord injury.
Apoptosis and its modulation
Apoptosis and cell necrosis
Cloning and characterisation the function of restriction-modification and other nuclease-coding genes from Streptomyces aureofaciens and Streptomyces antibioticus
Protein bioinformatics of starch-degrading enzymes and other glycoside hydrolases
Sodium dependent neurotransmitter transporters
Quantification of the ferromagnetic content in the biological structures
Biomembranes as an integrating element in cell physiology and pathology
Cell swelling induced secretion
DNA double-strand break repair in eukaryotes
Tissue and organ specificity of chemical carcinogens
Structure-function analysis of the DNA repair proteins
Bacteriophage BFK20 genome as a model for functional and structural analysis of unknown genes
Role of the stress genes/proteins involved in the preservation of virulence and protecting of enterohaemorrhagic E. coli against different stresses
Bioinformatics infrastructure in life sciences
A connection between stress, differentiation and pathogenicity of bacteria
Proteins involved in mitochondrial biogenesis
Engineering of biologically important proteins
Natural recombination of RNA viruses
Polyvalent vaccine incorporating Murine herpesvirus antigens as a tool for study of immune host response to human gammaherpesvirus infection
Population biology of metazoan parasites and application of genetic markers
Ticks and tick borne diseases
Bacterial cell division and differentiation
Preparation of biologically important oligo-saccharides by enzymic and chemoenzymic synthesis
Synthesis and Immunological Properties of Conjugates Containing Detoxified Bacterial Lipopolysaccharides bound to Immuno-modulant b-D-Glucan
Antioxidants in the elimination of developmental toxicity induced by oxidative stress and its consequences on the nervous system
Development and testing of prototype preventive retrovirus-based DNA vaccine against infection of more complex retroviruses
Overexpression of mdr1 – p-glycoprotein and multidrug resistance of neoplastic cells
Fungal membranes as the target in antimycotic therapy
Ischemia/reperfusion (e.g. stroke) induced injuries and their prevention by antioxidants derived from pyridoindol.
Evaluating the mechanisms of an eventual BSE transmission in susceptible and resistant sheep
Searching for the role of local renin –angiotensin system in adipose tissue
Magnetic Resonance Imaging evaluation in the human ageing with orientation to osteoporosis
Improved cardiac diagnostics by non-invasive assessment and model-based interpretation of the cardiac electric field
Genetic aspects of type 1 diabetes mellitus in children and adolescents
Intracellular calcium release channels and cardiovascular diseases
Modulation of single channel properties of mitochondrial K-ATP and permeability transition pore channels.
Adaptation of the heart on pressure overload during development of experimental hypertension. Remodeling.
Pathogenesis and protection of the myocardium mediated by the endothelium
Adaptation of the heart to stress: a novel strategy in management of cardiovascular diseases and diabetes
Increase of ischemic tolerance of the myocar-dium. The role of nitric oxide synthases.
Elucidation of the mechanisms and prevention of sudden cardiac death
The role of plasmalemmal ATPases in maintenance of the intracellular homeostasis of ions and termination of purinergic signal
Endogenous protection-related, Ca2+-involving signalling between subcellular membrane systems of the myocardium. Response to diverse pathological stimuli.
Ecology of tick-borne infections (tick-borne encephalitis virus, Lyme borreliosis and other tick-borne pathogens) and related genomics
Preparation and utilization of recombinant retrovirus vectors suitable for gene therapy of cancer
Mutations of RET Proto-Oncogene and Multiple Endocrine Neoplasia
Transcription factors and cancer
Modulation of carcinogenic effects of chemicals by antioxidants; study on mammalian cells in vitro and ex vivo
Hereditary cancer forms: biology and detection
Detection of the mutated K-ras oncogene – potential marker in early diagnostic of pancreatic carcinoma